Anti-fertility Effects of Carica papaya Linn: Methanol Leaf Extracts in Male Wistar Rats

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Effect of papaya (Carica papaya linn) on pregnancy and estrous cycle in albino rats of Wistar strain.

The antifertility effects of Carica papaya were investigated by feeding adult cycling and pregnant rats with different components of its fruits. No attempt was made to force-feed the animals. The results indicate that unripe fruits of papaya interrupt estrous cycle and induce abortions. The abortifacient property seems to decrease as the fruit becomes stale or ripe. Exogenous progesterone count...

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Protective Effect of Ethanol Leaf Extract of Carica papaya Linn (Caricaceae) in Alloxan-induced Diabetic Rats

Purpose: To investigate the ameliorative effect of ethanolic extract of Carica papaya leaves in alloxan induced diabetic rats. Methods: Rats were randomly divided into five groups of eight animals each. Group A (control) comprised normal healthy animals which were orally administered 1.0 ml of distilled water daily for 21 days while groups B – E consisted of alloxan-induced diabetic rats. Group...

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The protective effects of aqueous extract of Carica papaya seeds in paracetamol induced nephrotoxicity in male wistar rats.

BACKGROUND Oxidative stress plays a crucial role in the development of drug induced nephrotoxicity. The study aimed to determine the nephroprotective and ameliorative effects of Carica papaya seed extract in paracetamol-induced nephrotoxicity in rats. OBJECTIVES To carry out phytochemical screening of Carica papaya, measure serum urea, creatinine and uric acid and describe the histopathologic...

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Anti-Diabetic Activity of Terminalia catappa Linn. Leaf Extracts in Alloxan-Induced Diabetic Rats

In view of suggested anti diabetic potential, effect of aqueous and cold extracts of Terminalia Catappa Linn (Combretaceae) leaves, on fasting blood sugar levels and serum biochemical analysis in alloxan-induced diabetic rats was investigated. All the extracts of Terminalia Catappa produced a significant anti diabetic activity at dose levels of 1/5th of their lethal doses. Concurrent histologic...

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Preliminary hypoglycemic and hypolipidemic activities of the aqueous seed extract of Carica papaya Linn. in Wistar rats

The present study investigated the hypoglycemic, hypolipidemic and cardioprotective effects of 100 400 mg/kg/day/oral route of the aqueous seed extract of Carica papaya Linn (CPE) in normal male Wistar rats for 30 days. The rats, weighing between 120 and 150 g which were divided into groups I V of six rats each and were orally administered with 10 ml/kg/day of distilled water, 0.1 mg/kg/day of ...

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ژورنال

عنوان ژورنال: Journal of Pharmacology and Toxicology

سال: 2012

ISSN: 1816-496X

DOI: 10.3923/jpt.2013.35.41